The question of the etiology of chronic renal disease and of the cardiovascular lesions commonly associated with it has long interested investigators, and many attempts have been made to reproduce these conditions in animals. Although some of these efforts have met with a measure of success, hitherto the experimental disease has never closely duplicated that seen in man. An important advance toward a solution of some phases of this problem has recently been accomplished through the work of Goldblatt and his associates.1
These investigators were the first to reproduce in animals a condition closely resembling essential hypertension in man. This
THE EXPERIMENTAL PRODUCTION OF HYPERTENSION. Ann Intern Med. ;12:267–268. doi: 10.7326/0003-4819-12-2-267
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Published: Ann Intern Med. 1938;12(2):267-268.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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