RUSSELL L. CECIL, M.D., F.A.C.P.; D. MURRAY ANGEVINE, M.D.
Focal infection is a splendid example of a plausible medical theory which is in danger of being converted by its too enthusiastic supporters into the status of an accepted fact. Certainly the theory of focal infection has travelled a long way since it was first presented to the medical profession of America by Frank Billings1 in his classic contribution, "Chronic Focal Infections and Their Etiological Relations to Arthritis and Nephritis." This article was published in the Archives of Internal Medicine in 1912 and marks the first important contribution to the subject in this country. Today, 25 years after publication of
CECIL RL, ANGEVINE DM. CLINICAL AND EXPERIMENTAL OBSERVATIONS ON FOCAL INFECTION, WITH AN ANALYSIS OF 200 CASES OF RHEUMATOID ARTHRITIS(CLINICAL AND EXPERIMENTAL OBSERVATIONS ON FOCAL INFECTION, WITH AN ANALYSIS OF 200 CASES OF RHEUMATOID ARTHRITIS*). Ann Intern Med. 1938;12:577–584. doi: 10.7326/0003-4819-12-5-577
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Published: Ann Intern Med. 1938;12(5):577-584.
Rheumatoid Arthritis, Rheumatology.
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