ELMER C. BARTELS, M.D., F.A.C.P.
It has long been accepted that the liver undergoes pathologic changes in hyperthyroidism. A clinical manifestation of this liver damage is the occasional presence of jaundice of the hepatic type. Cameron and Karunaratne1 in a recent review of the subject (1935) gave Paul the credit for reporting the first case showing the association of liver injury with hyperthyroidism. He (Paul, 1865) described the case of a woman of 33 years with Graves' disease of four years' duration, who showed cirrhosis of the liver at postmortem examination. Other early observers of this relationship were Habershon (1874)2 who noted in a patient
BARTELS EC. LIVER FUNCTION IN HYPERTHYROIDISM AS DETERMINED BY THE HIPPURIC ACID TEST1. Ann Intern Med. ;12:652–674. doi: 10.7326/0003-4819-12-5-652
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Published: Ann Intern Med. 1938;12(5):652-674.
Endocrine and Metabolism, Thyroid Disorders.
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