IRVINE H. PAGE, M.D.
Physicians have long recognized that the clinical course of arterial hypertension is exceptionally variable. The lives of some patients appear to be little shortened by elevated blood pressure while others succumb within periods measurable in months. Volhard and Fahr (1914) emphasized these differences by the terms "benign" and "malignant," and Volhard pointed out that the benign form of hypertension may at any time turn malignant.
For some years the genesis of hypertension which showed signs of a rapidly fatal outcome was ascribed to the kidneys. Scant regard was paid the blood vessels in the remainder of the body. The morbid
IRVINE H. PAGE. A CLINICAL STUDY OF MALIGNANT HYPERTENSION(A CLINICAL STUDY OF MALIGNANT HYPERTENSION*). Ann Intern Med. 1939;12:978–1004. doi: 10.7326/0003-4819-12-7-978
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Published: Ann Intern Med. 1939;12(7):978-1004.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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