The demonstration that the polyneuritis of alcoholic addicts, like that of oriental beriberi, is caused by a deficiency of vitamin B1 and can be cured by the administration of this substance1 has aroused wide interest in the possible relation of dietary deficiencies to other types of degenerative diseases of the nervous system. There is strong evidence that a similar deficiency is responsible for the neuritis which may appear in patients on inadequate diets in such conditions as the early toxemias of pregnancy,2 protracted infections3 and serious gastrointestinal disturbances.4
The successful use of thiamin chloride in the treatment of these conditions
THE USE OF THIAMIN IN NEUROLOGICAL DISEASES. Ann Intern Med. 1939;12:1530–1532. doi: 10.7326/0003-4819-12-9-1530
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Published: Ann Intern Med. 1939;12(9):1530-1532.
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