BYRON D. BOWEN, M.D., F.A.C.P.; JAMES S. REGAN, M.D.; EDWARD C. KOENIG, M.D., F.A.C.P.
Both clinical and pathologic data support the view that vascular disease of the atherosclerotic type occurs earlier and is more extensive in the diabetic patient. Now that the proper use of insulin can almost eliminate uncomplicated acidosis as a cause of death and has greatly improved the status of the diabetic patient with an infection, attention, at the present time, is being directed toward the reduction of the intensity of atherosclerosis. The involvement of the muscular arteries, particularly the coronaries and those of the extremities, is responsible for the majority of deaths in older diabetics. Whatever the pathogenesis of this
BOWEN BD, REGAN JS, KOENIG EC. THE DEVELOPMENT OF ARTERIOSCLEROSIS IN THE DIABETIC, BASED ON THE STUDY OF A GROUP OF PATIENTS DURING TEN TO THIRTEEN YEARS1. Ann Intern Med. ;12:1996–2005. doi: 10.7326/0003-4819-12-12-1996
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Published: Ann Intern Med. 1939;12(12):1996-2005.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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