CARL A. DRAGSTEDT, Ph.D., M.D.
Probably the first definite suggestion that clinical allergy is related to experimental anaphylaxis was made by. Wolff-Eisner1 in 1905. Since that time numerous workers have noted both the fundamental similarities and the apparent differences between these reactions. The similarities may be stated in general terms as follows: In both instances reactions are produced by substances which may or may not have any inherent toxicity; the reactions occur in sensitive or susceptible individuals; the severity of the reaction depends more upon the degree of that susceptibility than upon either the inherent toxicity or the dose of the substance producing it; and
DRAGSTEDT CA. ANAPHYLAXIS AND ALLERGY1. Ann Intern Med. 1939;13:248–254. doi: 10.7326/0003-4819-13-2-248
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Published: Ann Intern Med. 1939;13(2):248-254.
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