WALTER LINCOLN PALMER, M.D.
The purpose of this paper is to consider briefly the relationship between benign and malignant gastric ulcers, the clinical differentiation of the two lesions, and the therapeutic implications.
A few years after Cruveilhier differentiated gastric ulcer from gastric carcinoma, Rokitansky described a case interpreted as showing the carcinomatous transformation of a benign ulcer. An enormous controversial literature has since developed regarding, first, the existence of carcinomatous degeneration in ulcer, and, secondly, the incidence of such a process. A critical review of the subject has led me to doubt the existence of such a transformation. The alleged evidence for such
PALMER WL. BENIGN AND MALIGNANT GASTRIC ULCERS: THEIR RELATION AND CLINICAL DIFFERENTIATION(BENIGN AND MALIGNANT GASTRIC ULCERS: THEIR RELATION AND CLINICAL DIFFERENTIATION*). Ann Intern Med. 1939;13:317–338. doi: 10.7326/0003-4819-13-2-317
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Published: Ann Intern Med. 1939;13(2):317-338.
Gastroenterology/Hepatology, Peptic Disease, Peptic Ulcer.
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