EDWIN E. OSGOOD, M.D.; MATHEW C. RIDDLE, M.D.; THOMAS J. MATHEWS, M.D.
This case is of interest for several reasons. The disease is uncommon. This patient received 43 transfusions totaling almost 22 liters of blood in 52 days. This prolonged life but produced polycythemia and enlargement of the spleen. Despite the amount of blood transfused the leukocyte and platelet counts remained at a relatively low level. No record was found of so large an amount of blood being given within this space of time.
A white school girl, 19 years of age, entered Multnomah County Hospital on October 26, 1937, complaining of weakness, pallor, shortness of breath, and bleeding from
OSGOOD EE, RIDDLE MC, MATHEWS TJ. APLASTIC ANEMIA TREATED WITH DAILY TRANSFUSIONS AND INTRAVENOUS MARROW; CASE REPORT1. Ann Intern Med. 1939;13:357–367. doi: 10.7326/0003-4819-13-2-357
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Published: Ann Intern Med. 1939;13(2):357-367.
Hematology/Oncology, Red Cell Disorders.
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