ALEXIS F. HARTMANN, M.D.
For quite some time we have been impressed with the value of alkali administration in the form of sodium r-lactate, not only as an emergency measure in relieving acutely developing acidosis in subjects with severe diarrhea, uncontrolled diabetes, or severe renal insufficiency, but also as a means of preventing the development or recurrence of severe acidosis in patients with renal defects not so severe as to be otherwise incompatible with fairly normal life. The purpose of this paper is threefold: (1) To review experiences with some patients in whom the renal lesion progressed to a fatal degree and to point
HARTMANN AF. CLINICAL STUDIES IN ACIDOSIS AND ALKALOSIS; USE AND ABUSE OF ALKALI IN STATES OF BICARBONATE DEFICIENCY DUE TO RENAL ACIDOSIS AND SULFANILAMIDE ALKALOSIS1. Ann Intern Med. 1939;13:940–956. doi: 10.7326/0003-4819-13-6-940
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Published: Ann Intern Med. 1939;13(6):940-956.
Endocrine and Metabolism, Nephrology.
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