EDWARD C. REIFENSTEIN JR., M.D.; EDWARD C. REIFENSTEIN SR., M.D., F.A.C.P.; JUSTIN W. MIGNAULT, M.D.; ANGELO J. RAFFAELE, M.D.
Acute poisoning with barbituric acid compounds ranks today as one of the commonest forms of acute drug intoxication; therefore, it has become a necessity for physicians to be familiar with the most satisfactory methods of treating this condition. A review of the recent clinical reports in the literature seems to indicate that picrotoxin, properly employed, is at present the most successful antidote for barbiturate poisoning. Table 1 summarizes the data of the cases in these reports. To them we are adding the two cases herein recorded, one of which is of unusual interest because the patient recovered after the ingestion
REIFENSTEIN EC, REIFENSTEIN EC, MIGNAULT JW, RAFFAELE AJ. PICROTOXIN IN THE TREATMENT OF ACUTE BARBITURATE POISONING; A REVIEW OF THE LITERATURE WITH REPORT OF TWO CASES1. Ann Intern Med. ;13:1013–1027. doi: 10.7326/0003-4819-13-6-1013
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Published: Ann Intern Med. 1939;13(6):1013-1027.
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