ELLIS B. FREILICH, M.D.; GEORGE C. COE, M.D.; NORMAN A. WIEN, M.D.
The chemotherapeutic effects of sulfanilamide (para-amino-benzene sulfonamide) in certain infectious diseases have been successfully demonstrated in humans and in experimental animals. Although the best results have been obtained in beta hemolytic streptococcic infections, it has been used in other conditions, as gonococcic urethritis, meningococcus meningitis, colon bacillus pyelitis, brucellosis, etc., with varying degrees of success. Intensive studies have been carried out by Long and Bliss, who in a recent article1 give an excellent bibliography of investigations in this field.
However, the possible use of sulfanilamide in chronic granulomatous infections has so far received little if any attention. In January 1938
FREILICH EB, COE GC, WIEN NA. THE USE OF SULFANILAMIDE IN PULMONARY TUBERCULOSIS; PRELIMINARY REPORT(THE USE OF SULFANILAMIDE IN PULMONARY TUBERCULOSIS; PRELIMINARY REPORT*). Ann Intern Med. 1939;13:1042–1045. doi: 10.7326/0003-4819-13-6-1042
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Published: Ann Intern Med. 1939;13(6):1042-1045.
Infectious Disease, Mycobacterial Infections, Pulmonary Tuberculosis, Pulmonary/Critical Care.
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