J. SHIRLEY SWEENEY, M.D., Sc.D., F.A.C.P.; L. E. ALLDAY, M.D.
In an issue of the Journal of the American Medical Association there appeared experimental studies, case reports and an editorial concerning sulfanilamide. Two of these papers1, 2 dealt with the leukocytic response to sulfanilamide and its mode of action. In an interesting and cogent extension of the subject were two case reports3, 4 of fatal intoxication following administration of the drug. Reference was made to two other reports of fatal cases. The subject was reviewed editorially, and one is reminded that the Council on Pharmacy and Chemistry originally advised periodical microscopic examinations of blood of patients taking sulfanilamide.
SWEENEY JS, ALLDAY LE. GRANULOCYTOPENIA FROM SULFANILAMIDE WITH UNUSUAL BLOOD CRISIS AND RECOVERY; CASE REPORT1. Ann Intern Med. 1940;13:1241–1243. doi: 10.7326/0003-4819-13-7-1241
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Published: Ann Intern Med. 1940;13(7):1241-1243.
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