In 1895 Faber1 in Denmark first called attention to the association of pernicious anemia with a stricture of the small intestine. He postulated that absorption of a poison from the stagnant bowel contents above the stricture was responsible for the anemia. Meulengracht2 added weight to this theory in 1921 when he found at the autopsy of a case of severe "pernicious anemia" associated with a tuberculous stricture of the ileum that the entire small intestine was heavily infected with bacteria. Comparing his case with five similar cases previously reported he arrived at the following conclusions: (1) pernicious anemia may develop
INTESTINAL STASIS AND MACROCYTIC ANEMIA. Ann Intern Med. ;13:1253–1254. doi: 10.7326/0003-4819-13-7-1253
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Published: Ann Intern Med. 1940;13(7):1253-1254.
Gastroenterology/Hepatology, Hematology/Oncology, Red Cell Disorders.
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