PAUL H. NOTH, M.D.; DWIGHT L. WILBUR, M.D., F.A.C.P.
For a long time clinicians and surgeons have appreciated the fact that a close relationship exists between loss of gastric and duodenal content by vomiting or through a fistula and changes in the chemical composition of the plasma of the blood. The importance of recognizing these changes in patients suffering from pyloric obstruction in whom surgical treatment is to be carried out has been amply proved by the reduction in mortality which has followed adequate preoperative preparation of patients. While the mechanisms leading to some of the chemical changes, for example, elevation of the values for urea content of the
NOTH PH, WILBUR DL. CHEMICAL CHANGES IN THE BLOOD OF PATIENTS WITH PYLORIC OBSTRUCTION1. Ann Intern Med. ;13:1285–1296. doi: 10.7326/0003-4819-13-8-1285
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Published: Ann Intern Med. 1940;13(8):1285-1296.
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