S. S. LICHTMAN, M.D.
Several factors are known to influence erythrocyte sedimentation rate. Most important among these are plasma fibrinogen and globulins. Variations in sedimentation rate have been correlated with changes in the plasma proteins.1-7 The liver plays a rôle in the regeneration of plasma proteins8, 9, 10 and this function is impaired by infection.11-14 An underlying hepatitis was empirically assumed by Gram15 to be responsible for abnormal rates under all conditions. The rôle of the liver as one of the factors influencing erythrocyte sedimentation was also suggested by Snapper.16 In frank liver disease, however, consistent changes in sedimentation rate have not been observed.17,
LICHTMAN SS. THE INFLUENCE OF INTRAVENOUS GLUCOSE INJECTIONS ON ABNORMAL ERYTHROCYTE SEDIMENTATION SPEED IN RELATION TO ACTIVITY OF INFECTION1. Ann Intern Med. 1940;13:1297–1305. doi: 10.7326/0003-4819-13-8-1297
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Published: Ann Intern Med. 1940;13(8):1297-1305.
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