W. T. DAWSON
Because of the existence of individual variability in response to drugs, no method can be devised for determining accurately in advance the proper dosages of drugs for individuals. Average doses, suitable for large groups of adult patients, have been worked out empirically and are printed in pharmacopoeias. This paper is concerned with a survey of methods by which drug dosage might be modified for age and size of individual.
It is natural to proportion dosage according to size of patient, and I suppose it was done even by our Stone Age ancestors. We have today a rule for doing this,
DAWSON WT. RELATIONS BETWEEN AGE AND WEIGHT AND DOSAGE OF DRUGS1. Ann Intern Med. 1940;13:1594–1615. doi: 10.7326/0003-4819-13-9-1594
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Published: Ann Intern Med. 1940;13(9):1594-1615.
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