FRED M. SMITH, M.D., F.A.C.P.
The fact that it is often difficult or perhaps impossible to correlate the pathology and symptoms of coronary artery disease has led to a great deal of discussion and numerous explanations have been proposed. Developments during recent years, however, have contributed much to better understanding of the problem.
Certain aspects of the pathology have a particular bearing on the diverse symptoms. In the first place, it is generally known that the heart may be normal in size in the presence of extensive sclerosis of the coronary arteries. Thus, in 113 cases analyzed by Nathanson,1 selected because they presented advanced stage
SMITH FM. CONCERNING THE CORRELATION OF THE PATHOLOGY AND SYMPTOMS OF CORONARY ARTERY DISEASE1. Ann Intern Med. ;14:65–71. doi: 10.7326/0003-4819-14-1-65
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Published: Ann Intern Med. 1940;14(1):65-71.
Cardiology, Coronary Heart Disease.
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