EDWARD BIGG, M.D.
A palpable spleen has long been accepted as an expected finding in the physical examination of a patient suffering from pernicious anemia. Although Sturgis11 reported the spleen to be rarely palpable and Minot7 pointed out that it was palpable in only 5 per cent of his cases, the majority of standard textbooks and monographs on pernicious anemia give the incidence as from 20 to 50 per cent.
Evans3 reported the spleen to be palpable in 20 per cent of his cases. In McCarty's6 series of 51 cases the spleen was palpably enlarged in 45 per cent. Cornell2 stated that the
BIGG E. SPLEEN SIZE IN PERNICIOUS ANEMIA1. Ann Intern Med. ;14:277–280. doi: 10.7326/0003-4819-14-2-277
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Published: Ann Intern Med. 1940;14(2):277-280.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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