CURTIS F. GARVIN, M.D.; HERBERT S. REICHLE, M.D.
The use of a low salt diet as a diagnostic test in doubtful cases of Addison's disease was suggested by Harrop and his coworkers1 in 1933. Two to five days after beginning the restriction of sodium chloride signs of relapse and characteristic concomitant alterations in the blood occur. That the test is dangerous has been recognized. Cortical extract, as well as intravenous salt solution, must be immediately available in event of a serious crisis.
This communication reports a sudden death occurring in a patient with Addison's disease during the period of a salt restriction test. Another report of death, presumably
GARVIN CF, REICHLE HS. DEATH PRESUMABLY DUE TO THE USE OF THE SALT RESTRICTION TEST IN THE DIAGNOSIS OF ADDISON'S DISEASE1. Ann Intern Med. ;14:323–324. doi: 10.7326/0003-4819-14-2-323
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Published: Ann Intern Med. 1940;14(2):323-324.
Adrenal Disorders, Endocrine and Metabolism.
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