R. R. SNOWDEN, M.D., F.A.C.P.
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The term "physiological adjustment," as here used, refers to the way in which the physiological processes respond to the demands of carbohydrate metabolism. In the normal individual this adjustment is so prompt and efficient that even widely varying amounts of glucose are utilized almost immediately; in fact it is difficult to break through a normal glucose tolerance. In the diabetic, on the other hand, physiological adjustment is sluggish and lacks quick mobility; therefore, it can become fully effective only when the demands upon it are reasonable, and are maintained unchanged day after day until adjustment has had time to complete
SNOWDEN RR. THE IMPORTANCE OF ALLOWING TIME FOR "PHYSIOLOGICAL ADJUSTMENT" IN ESTABLISHING THE DIET IN DIABETES1. Ann Intern Med. 1940;14:789–794. doi: 10.7326/0003-4819-14-5-789
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Published: Ann Intern Med. 1940;14(5):789-794.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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