J. KAUFMANN, M.D., F.A.C.P.; L. LOWENSTEIN, M.D.
Many contributions have been made to the study of acute leukosis. Confusion still characterizes many features of this disease. We wish to present a clinico-pathologic study of 40 cases of acute leukosis observed in the Royal Victoria Hospital of Montreal in the past 20 years. We hope that this study will prove helpful in reëvaluating the wide diversity of opinions expressed.
We would define acute leukosis as a fatal disease of short duration, characterized by an untoward proliferation of primitive leukocytes in the hematopoietic tissue of the bone-marrow, lymph nodes, and spleen, with delivery of these cells to the peripheral
KAUFMANN J, LOWENSTEIN L. A STUDY OF THE ACUTE LEUKOSES1. Ann Intern Med. ;14:903–915. doi: 10.7326/0003-4819-14-5-903
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Published: Ann Intern Med. 1940;14(5):903-915.
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