C. WESLER SCULL, PH.D.; RALPH PEMBERTON, M.D., F.A.C.P.
Studies conducted in this laboratory on the protein fractions in the sera of arthritics clearly show that moderate and sometimes marked hyperglobulinemia is a significant feature among certain classes of arthritic subjects.6 Associated with the increase in serum globulin there is an elevation in the fibrinogen of the corresponding plasma. These results are in substantial agreement with observations made by Aldred-Brown and Monroe1 and by Davis.3 Recognition of the presence of these features in a given case is of practical importance, inasmuch as an elevation in the level of the globulin or fibrinogen in the blood shows the presence
SCULL CW, PEMBERTON R. THE FORMOL-GEL REACTION IN BLOOD OF PATIENTS WITH CHRONIC RHEUMATOID DISEASES1. Ann Intern Med. 1940;14:993–1000. doi: 10.7326/0003-4819-14-6-993
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Published: Ann Intern Med. 1940;14(6):993-1000.
Rheumatoid Arthritis, Rheumatology.
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