VERNER B. CALLOMON, M.D.; WILLIAM E. GOODPASTOR, M.D.
In view of the remarkable therapeutic effects obtained with sulfanilamide and sulfapyridine it was to be expected that investigators would direct their efforts to the preparation of derivatives or modifications of these drugs which, while retaining their therapeutic activity, would be free of the undesirable side-effects so commonly encountered in their use. One of the products recently made available is sulfathiazole (2-sulfanilamidethiazole), which was independently synthesized by Fosbinder and Walter,1 and Lott and Bergeim.2
Several reports on the pharmacology and experimental use of this drug in animals and man have recently been published. From these the following observations may be
CALLOMON VB, GOODPASTOR WE. SULFATHIAZOLE IN THE TREATMENT OF PNEUMOCOCCUS PNEUMONIA1. Ann Intern Med. ;14:1024–1031. doi: 10.7326/0003-4819-14-6-1024
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Published: Ann Intern Med. 1940;14(6):1024-1031.
Infectious Disease, Pneumonia, Pulmonary/Critical Care, Streptococcal Infections.
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