SIDNEY KAHN, M.D.; MAXWELL SPRING, M.D.
Obstruction to the blood flow through the hepatic veins leads to a pathological-clinical entity known as Chiari's syndrome, of which there have been reported, as far as we could determine, approximately 60 cases, and which combines the clinical picture of portal obstruction and hepatic degeneration. The disease is undoubtedly often overlooked because of its similarity to the late stages of atrophic cirrhosis (Laennec's).
We are reporting a case because of its rarity, and because the clinical study included venous pressure determinations which aided in the diagnosis.
In 1846, Budd commented on cases of intrahepatic abscesses that involved one of
KAHN S, SPRING M. THROMBOSIS OF THE HEPATIC VEINS—CHIARI'S SYNDROME; REPORT OF A CASE WITH BIOPSY AND VENOUS PRESSURE DETERMINATION1. Ann Intern Med. 1940;14:1075–1083. doi: 10.7326/0003-4819-14-6-1075
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Published: Ann Intern Med. 1940;14(6):1075-1083.
Gastroenterology/Hepatology, Liver Disease.
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