S. S. LICHTMAN, M.D.
The endocrines may influence the functions of the liver, mainly the glycogenic function.1, 2, 3 Claude Bernard regarded glycogen as an internal secretion product of the liver and recognized connections between this substance and other endocrine products.
Experimental data, pathological observations, clinical jaundice in patients with exophthalmic goiter, and liver function studies establish the fact that the liver is frequently damaged in hyperthyroidism.
The evidence in the literature upon which the connection between hyperthyroidism and liver damage has been established will be presented as follows:
(1) experimental; (2) anatomic changes in the liver; (3) clinical cases of
LICHTMAN SS. LIVER FUNCTION IN HYPERTHYROIDISM, WITH SPECIAL REFERENCE TO THE GALACTOSE TOLERANCE TEST1. Ann Intern Med. ;14:1199–1215. doi: 10.7326/0003-4819-14-7-1199
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Published: Ann Intern Med. 1941;14(7):1199-1215.
Endocrine and Metabolism, Thyroid Disorders.
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