MILTON KISSIN, M.D.; ABRAHAM G. COHEN, M.D.
Knowledge of the primary tuberculous complex dates from the work of Kuss (1898), Albrecht (1909), and Ghon (1912).2 The pulmonary component of the complex, which is a zone of caseous pneumonia surrounding the site of the initial infection, is known in modern medicine as the primary or Ghon focus (tubercle). It is usually located subpleurally and is often very small, generally not larger than a bean, rarely larger than a hazel-nut. Over 95 per cent of cases have only one focus, and cases having more than two are very rare. It is most often found in the lower portion of
KISSIN M, COHEN AG. LARGE HEALED TUBERCULOUS FOCUS (PROBABLY PRIMARY) SIMULATING METASTATIC CARCINOMA OF THE LUNG1. Ann Intern Med. 1941;14:1216–1224. doi: 10.7326/0003-4819-14-7-1216
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Published: Ann Intern Med. 1941;14(7):1216-1224.
Hematology/Oncology, Infectious Disease, Lung Cancer, Mycobacterial Infections, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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