SAMUEL F. HAINES, M.D., F.A.C.P.; THOMAS B. MAGATH, M.D., F.A.C.P.; MARSCHELLE H. POWER, Ph.D.
For many years it has been known that disturbances in the function of the liver might occur in severe exophthalmic goiter. Jaundice has been recognized to be a serious, and usually late, development in the crisis of exophthalmic goiter.
In cases of this type livers have frequently showed changes designated by Robertson1 as "subacute yellow atrophy." In 1933, Weller2 found a patchy, chronic parenchymatous, interlobar hepatitis in many of the livers of patients with exophthalmic goiter. In the same year, Beaver and Pemberton3 studied the livers of 107 patients with exophthalmic goiter and found acute degenerative lesions, simple atrophy, or
HAINES SF, MAGATH TB, POWER MH. THE HIPPURIC ACID TEST IN HYPERTHYROIDISM1. Ann Intern Med. 1941;14:1225–1232. doi: 10.7326/0003-4819-14-7-1225
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Published: Ann Intern Med. 1941;14(7):1225-1232.
Endocrine and Metabolism, Thyroid Disorders.
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