MAURICE BRUGER, M.D.; MAURICE R. CHASSIN, M.D.
The investigations of Goldblatt1 have focused attention on renal ischemia as one of the etiological agents responsible for hypertension. Ample clinical confirmation of this concept has appeared in the recent literature2-15 and not a few of the cases cited are counterparts of Goldblatt's experiments on dogs and monkeys. It must be conceded, however, that necropsies on most patients with essential hypertension fail to reveal gross renal ischemia. In 1939, Christian, Schlesinger and Myers16 showed that the perfusion flow through kidneys obtained at postmortem examinations of patients having essential hypertension was decidedly less than the flow through kidneys of persons with
BRUGER M, CHASSIN MR. THE CHOLESTEROL CONTENT OF THE RENAL ARTERIES AND OF THE THORACIC AORTA IN RELATION TO HYPERTENSION AND VASCULAR PATHOLOGY1. Ann Intern Med. 1941;14:1756–1767. doi: 10.7326/0003-4819-14-10-1756
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Published: Ann Intern Med. 1941;14(10):1756-1767.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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