HILDAHL I. BURTNESS, M.D.; ALFRED E. KOEHLER, M.D.; JAMES H. SAINT, M.D., F.R.C.S. (Eng.), F.A.C.S.
At the present time, the comparative rarity of cases of adenoma of the islets of Langerhans and the short time which has elapsed since the discovery of the condition and of its clinical significance, render each case of extreme interest to the medical men concerned in its diagnosis and in the discovery and removal of the tumor at operation. Moreover, our knowledge of the condition is still in the stage when it can be furthered by careful studies in any given case.
Shortly after Banting and Best2 announced their discovery of insulin in 1922 the clinical syndrome associated with hypoglycemia
BURTNESS HI, KOEHLER AE, SAINT JH. HYPERINSULINISM DUE TO ADENOMA OF THE ISLETS OF LANGERHANS: CASE REPORT WITH METABOLIC STUDIES BEFORE AND AFTER REMOVAL OF TUMOR1. Ann Intern Med. ;14:1915–1932. doi: 10.7326/0003-4819-14-10-1915
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Published: Ann Intern Med. 1941;14(10):1915-1932.
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