MICHAEL J. LEPORE
During the course of a study of sprue and allied deficiency states,1 low or "flat" oral glucose tolerance curves were observed very frequently in the affected individuals. This was not a novel observation, for other observers had had the same experience, and furthermore, had suggested that this finding serve as a diagnostic aid in the recognition of sprue.2, 3
A review of the pertinent literature revealed considerable difference of opinion on the interpretation of the low oral glucose tolerance curve.2, 4, 5, 6 It was felt that before relying too greatly upon the contour of the curve as a diagnostic
LEPORE MJ. THE CLINICAL SIGNIFICANCE OF THE LOW OR "FLAT" ORAL GLUCOSE TOLERANCE CURVE1. Ann Intern Med. ;14:2008–2013. doi: 10.7326/0003-4819-14-11-2008
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Published: Ann Intern Med. 1941;14(11):2008-2013.
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