JOHN P. ANDERSON, M.D., F.A.C.P.
The clinical use of picrotoxin in combating acute barbiturate intoxication is sufficiently new that an experience with 20 cases of this type, observed during the last year and a half, may prove of value. In recent years, the taking of large quantities of barbiturates of various kinds has become an increasingly popular method of attempting suicide. In all of the cases to be described, the barbiturate was taken with suicidal intent, and the patients were seen and treated on the medical services of St. Vincent's Charity and Glenville Hospitals, in Cleveland.
Although Browne1 discovered, in 1875, that picrotoxin protected rabbits
ANDERSON JP. THE TREATMENT OF BARBITURATE INTOXICATION WITH SPECIAL REFERENCE TO PICROTOXIN; A REPORT OF 20 CASES1. Ann Intern Med. ;14:2037–2046. doi: 10.7326/0003-4819-14-11-2037
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Published: Ann Intern Med. 1941;14(11):2037-2046.
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