HAROLD J. MAGNUSON, M.D.; B. O. RAULSTON, M.D., F.A.C.P.
The use of massive doses of arsenicals, given by the intravenous drip method, in the treatment of syphilis by Hyman, Chargin, Leifer and their co-workers1 has stimulated renewed interest and effort directed toward improvement of the generally accepted plans for treatment of this disease. The advantages of reducing the time during which treatment must be continued consecutively and of rapidly stopping the possibility of spreading the disease are self evident. The need of information concerning the distribution of arsenic in the body following injection of large amounts within short periods is conspicuous. The relationship between concentrations of arsenic and its
MAGNUSON HJ, RAULSTON BO. THE CONCENTRATION OF ARSENIC IN TISSUES AND THE EXCRETION OF ARSENIC BY EXPERIMENTAL ANIMALS FOLLOWING INTRAVENOUS INJECTION OF MASSIVE DOSES OF MAPHARSEN1. Ann Intern Med. ;14:2199–2209. doi: 10.7326/0003-4819-14-12-2199
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Published: Ann Intern Med. 1941;14(12):2199-2209.
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