J. C. ZILLHARDT, M.D.; KEITH MACLEAN, M.D.; WILLIAM P. MURPHY, M.D.
By supplying sufficient amounts of anti-pernicious anemia substance it is possible to control the neural disturbances of uncomplicated Addisonian anemia. Certain residual neural manifestations are apt to remain, however, in spite of adequate liver therapy. This is particularly true in patients with advanced nervous system involvement and in those who have not been adequately treated at the onset.
Considerable thought has been given the various vitamins1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 in connection with pernicious anemia and its associated neural disturbances. At the blood clinic of the Peter Bent Brigham Hospital interest became focused on
ZILLHARDT JC, MACLEAN K, MURPHY WP. THE EFFECT OF THIAMIN ON THE RESIDUAL NEURAL DISTURBANCES OF TREATED PERNICIOUS ANEMIA1. Ann Intern Med. ;15:33–43. doi: 10.7326/0003-4819-15-1-33
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Published: Ann Intern Med. 1941;15(1):33-43.
Hematology/Oncology, Red Cell Disorders.
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