MAX M. STRUMIA, M.D.; JOHN J. MCGRAW, M.D.
Experimentally plasma or serum was used as far back as 1871 by Bowditch1 and a year later by Luciani.2 A very extensive bibliography of the earlier experimental works on serum and plasma is contained in Amberson's review.3 In 1918 Ward,4 a captain in the British army, made a terse appeal for the use of citrated plasma in the treatment of emergencies at the clearing stations, and briefly outlined the advantages over whole blood.
As far as we know his appeal was not answered, and probably the first extensive clinical use of serum and plasma was begun by one of us
STRUMIA MM, MCGRAW JJ. THE DEVELOPMENT OF PLASMA PREPARATIONS FOR TRANSFUSIONS(THE DEVELOPMENT OF PLASMA PREPARATIONS FOR TRANSFUSIONS*). Ann Intern Med. 1941;15:80–88. doi: 10.7326/0003-4819-15-1-80
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Published: Ann Intern Med. 1941;15(1):80-88.
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