ROBERT B. AIRD, M.D.
The term "malignant exophthalmos" designates the progressive and alarming proptosis which occurs in a small group, usually after thyroidectomy and in the presence of a low basal metabolic rate. Unless relieved by operative decompression of the bony orbit, as devised by Naffziger,1 a high percentage of these patients develop corneal ulceration, infection, and fatal intracranial extension of the orbital cellulitis. The pathologic changes and immediate cause of the exophthalmos occurring in these patients were described in detail in previous reports.1 In brief, the extraocular muscles were found to be enlarged from three to eight times. Grossly, the musculature of the
AIRD RB. EXPERIMENTAL EXOPHTHALMOS AND ASSOCIATED MYOPATHY INDUCED BY THE THYROTROPIC HORMONE1. Ann Intern Med. 1941;15:564–581. doi: 10.7326/0003-4819-15-3-564
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Published: Ann Intern Med. 1941;15(3):564-581.
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