CHARLES C. HIGGINS, M.D.
In 1836, Mercier1 first mentioned ulcerations of the floor of the bladder causing perforation. Lawson Tait2 in 1870 discussed a similar lesion and cited an additional case. Fenwick3 in 1896 described in detail, "simple ulcer of the bladder," and mentioned the sudden onset of the disease characterized clinically by increased frequency of urination, dysuria, and intermittent hematuria.
As some confusion still exists as to the lesion which should be classified as a Hunner ulcer, it is of interest to refer to Hunner's original description in 1914.4 He stated that the ulcer is found on the vertex, summit, or free portion
HIGGINS CC. HUNNER ULCER OF THE BLADDER (REVIEW OF 100 CASES)1. Ann Intern Med. ;15:708–715. doi: 10.7326/0003-4819-15-4-708
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Published: Ann Intern Med. 1941;15(4):708-715.
Nephrology, Urological Disorders.
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