WALLACE M. YATER, M.D., F.A.C.P.; EDWARD W. NICKLAS, M.D.
Cold allergy has been known since 1866, when Bourden1 described urticaria and syncope due apparently to cold. However, in 1872 Blachez2 gave the first classical description of urticaria from cold. Since then several other writers have reported cases of this form of allergy. Since 1924 Duke3 has written voluminously on this subject, describing various forms of physical allergy, which he found to be not uncommon. He suggested the possibility that a histamine-like substance might be liberated locally and be responsible in some instances. Lewis4 later showed the probable existence of such a substance. In 1929 Horton and Brown5 reported a
YATER WM, NICKLAS EW. COLD ALLERGY: REPORT OF AN UNUSUAL CASE1. Ann Intern Med. ;15:743–748. doi: 10.7326/0003-4819-15-4-743
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Published: Ann Intern Med. 1941;15(4):743-748.
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