FRANK L. HORSFALL JR., M.D.
Investigations of influenza have been beset with serious difficulties since first they were begun. Acute upper respiratory diseases tend to resemble each other very closely and, as is well known, their classification on clinical grounds has not been very successful. One of the chief difficulties is the lack of definite objective signs, except for fever and minor alterations in the appearance of the mucosa of the upper respiratory tract. Unfortunately, there is no sharp line between the symptomatology of a severe common cold, sporadic grippe, and influenza. The manifestations of these symptom-complexes shade imperceptibly one into another, and the difficulties
HORSFALL FL. INFLUENZA1. Ann Intern Med. 1941;15:811–816. doi: 10.7326/0003-4819-15-5-811
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Published: Ann Intern Med. 1941;15(5):811-816.
Infectious Disease, Influenza, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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