WILLIAM H. SEBRELL, M.D., F.A.C.P.
The symptoms caused by deficiencies in various members of the vitamin B complex probably constitute our greatest medical problem in the deficiency field. There are eight known substances which may be called members of the vitamin B complex. These are thiamin, riboflavin, nicotinic acid, pyridoxine, pantothenic acid, p-aminobenzoic acid, choline and inositol. At least four of these appear to be needed by man. These are thiamin, riboflavin, nicotinic acid and pyridoxine. Deficiencies in the remaining known members of the B complex have been shown to cause various symptoms in experimental animals.
It has been shown that a deficiency in pantothenic
SEBRELL WH. THE CLINICAL SYMPTOMS AND SIGNS OF VITAMIN B COMPLEX DEFICIENCY1. Ann Intern Med. ;15:953–958. doi: 10.7326/0003-4819-15-6-953
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Published: Ann Intern Med. 1941;15(6):953-958.
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