FRANCIS H. CHAFEE, M.D., F.A.C.P.
Since Keeney1 in 1938 first reported the use of a slowly absorbed epinephrine preparation, allergists have found that the use of epinephrine in oil is of great value in controlling intractable asthma. Epinephrine in peanut oil is now available commercially. Although there are few reports in the literature definitely indicating that peanut oil may act as an atopen, there are records of unusual reactions to this preparation.
In 1939 Keeney2 reported one instance in which urticaria developed after daily use of epinephrine in peanut oil for six weeks. This occurred along with a flare-up of an old sinusitis, and whether
CHAFEE FH. SENSITIVITY TO PEANUT OIL WITH THE REPORT OF A CASE1. Ann Intern Med. ;15:1116–1117. doi: 10.7326/0003-4819-15-6-1116
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Published: Ann Intern Med. 1941;15(6):1116-1117.
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