L. A. JULIANELLE
In an earlier communication1 published in this journal, a preliminary account was given of the experimental treatment of staphylococcal septicemia with specific antibacterial serum. Obtained from rabbits following immunization with intact, formalinized organisms, the antiserum was particularly prepared to contain high titers of antibody capable of reacting with the somatic carbohydrate extractable from pathogenic (Type A) staphylococci.2 The rationale for the therapeutic expectancy of such an antiserum was based on the theoretical considerations arising from the observation that precipitins for the carbohydrate in question are demonstrable in the sera of those patients only who have recovered from severe, generalized infection.3
JULIANELLE LA. OBSERVATIONS ON THE SPECIFIC TREATMENT (TYPE A ANTISERUM) OF STAPHYLOCOCCAL SEPTICEMIA; SECOND REPORT1. Ann Intern Med. 1942;16:303–326. doi: 10.7326/0003-4819-16-2-303
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Published: Ann Intern Med. 1942;16(2):303-326.
Infectious Disease, Multi-Organ Failure and Sepsis, Pulmonary/Critical Care.
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