M. SOKOLOW, M.D.; H. B. WEINBERG, M.D.; J. L. PLAUT, M.D.; L. N. KATZ, M.D.
Although digitalis is one of the oldest drugs used in specific cardiac therapy, and probably the most widely used, there is still some dispute as to its indications and value under various circumstances. Opinions range from those recommending that digitalis be administered in all cases of heart disease (Christian,1 Cloetta2) to those stating that digitalis has striking value only in cases of auricular fibrillation, and here only by slowing the ventricular rate (Lewis3). That digitalis slows the ventricular rate in auricular fibrillation has been conclusively demonstrated (Mackenzie,5 Cushny4). This may improve the efficiency of the heart and produce striking relief
SOKOLOW M, WEINBERG HB, PLAUT JL, KATZ LN. DIGITALIS IN THE PREVENTION OF RECURRENT CARDIAC FAILURE IN PATIENTS WITH SINUS RHYTHM1. Ann Intern Med. ;16:427–437. doi: 10.7326/0003-4819-16-3-427
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Published: Ann Intern Med. 1942;16(3):427-437.
Cardiology, Heart Failure.
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