NORMAN Q. BRILL, M.D.; HERTA SEIDEMANN, M.D.
The clinical observation that attacks of petit mal can be induced by hyperventilation led us to the utilization of this procedure as a routine measure in electroencephalographic examination of patients with known or suspected epilepsy. Since the casual electroencephalographic examination of such patients in the interval between attacks frequently resulted in normal records, it was felt that a higher percentage of positive records could be obtained if the patients were hyperventilated during the examination. This expectation was borne out not only in petit mal epilepsy but also in grand mal, but, because of previously reported changes in the electroencephalogram produced
BRILL NQ, SEIDEMANN H. ELECTROENCEPHALOGRAPHS CHANGES DURING HYPERVENTILATION IN EPILEPTIC AND NON-EPILEPTIC DISORDERS1. Ann Intern Med. ;16:451–461. doi: 10.7326/0003-4819-16-3-451
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Published: Ann Intern Med. 1942;16(3):451-461.
Neurology, Seizure Disorders.
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