NORBERT ENZER, M.D., F.A.C.P.; ERNST SIMONSON, M.D.; SAMUEL S. BLANKSTEIN, M.D.
Patients with circulatory insufficiency from heart disease and hypertension fatigue easily, not only in heavy or moderate muscular work, but also in types of light muscular work, in mental work and even in resting condition. This cannot be explained by the circulatory insufficiency alone; the increase of the oxygen consumption during those types of work is very slight, and these patients are still able to increase the cardiac minute volume more than would be necessary to cover the slightly increased demands for oxygen consumption and transportation.
This question has some practical significance. There are several million cardiac patients with slight
ENZER N, SIMONSON E, BLANKSTEIN SS. FATIGUE OF PATIENTS WITH CIRCULATORY INSUFFICIENCY, INVESTIGATED BY MEANS OF THE FUSION FREQUENCY OF FLICKER1. Ann Intern Med. ;16:701–707. doi: 10.7326/0003-4819-16-4-701
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Published: Ann Intern Med. 1942;16(4):701-707.
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