NORMAN M. KEITH, M.D.; ARNOLD E. OSTERBERG, PH.D.; HOWARD B. BURCHELL, M.D.
During the last few years both the physiologist and the clinician have discovered many new facts regarding the metabolism of potassium. Several factors have stimulated recent studies in this subject and among these have been the availability of accurate microchemical methods for the estimation of potassium in body fluids, the application of physiologic principles to the study of certain clinical syndromes, and a desire to establish more clearly the dividing line between the pharmacologic and toxic effects of potassium salts.
The problem of toxicity has been confused in the past by conflicting results obtained in two types of studies. The
KEITH NM, OSTERBERG AE, BURCHELL HB. SOME EFFECTS OF POTASSIUM SALTS IN MAN1. Ann Intern Med. ;16:879–892. doi: 10.7326/0003-4819-16-5-879
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Published: Ann Intern Med. 1942;16(5):879-892.
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