GEORGE W. THORN, F.A.C.P.; SAMUEL S. DORRANCE; EMERSON DAY
The immediate and favorable response of patients with Addison's disease to synthetic desoxycorticosterone acetate therapy is now well established.1, 2, 3, 4, 5 The effect which treatment with desoxycorticosterone acetate will have on the life expectancy of patients with Addison's disease cannot be stated at this early date, although our experience indicates that there has been a considerable reduction in mortality rate during the first 18 months of therapy.
The present report summarizes our experience with synthetic desoxycorticosterone acetate therapy during the past three years. In this period 158 patients with classical signs and symptoms of Addison's disease have
THORN GW, DORRANCE SS, DAY E. ADDISON'S DISEASE: EVALUATION OF SYNTHETIC DESOXYCORTICOSTERONE ACETATE THERAPY IN 158 PATIENTS1. Ann Intern Med. ;16:1053–1096. doi: 10.7326/0003-4819-16-6-1053
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Published: Ann Intern Med. 1942;16(6):1053-1096.
Adrenal Disorders, Endocrine and Metabolism.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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