M. S. REDNICK, M.D., F.A.C.P.
The subject of the systolic murmur is still a broad and rather unsettled phase of cardiology, and although much has been added to the general knowledge concerning the etiology and mechanics of this murmur, full progress and complete understanding in this important field have not kept pace with advances made in other branches of medicine. A search of the literature reveals a rather surprising number of divergent views which have been expressed regarding the cause, significance and interpretation of the systolic murmur.
The factors entering into the production of a murmur are well brought out by Sprague2 who states "that
REDNICK MS. A PATHOLOGICAL STUDY OF THE SIGNIFICANCE OF THE SYSTOLIC MURMUR(A PATHOLOGICAL STUDY OF THE SIGNIFICANCE OF THE SYSTOLIC MURMUR*). Ann Intern Med. 1942;16:1197–1205. doi: 10.7326/0003-4819-16-6-1197
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Published: Ann Intern Med. 1942;16(6):1197-1205.
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