EDWARD C. ROSENOW, M.D.; HAYES W. CALDWELL, M.D.
We have had opportunity to study the etiology of encephalitis as it occurred during the summer and autumn of 1941 and to observe patients while they were under treatment with the encephalitis antistreptococcic serum.
The patients with encephalitis observed in this epidemic presented striking similarities in symptomatology and appearance. Headache, nausea and vomiting with fever were the cardinal symptoms. Patients who had the severe forms of the disease were striking in appearance; not infrequently the patients were irrational, many were lethargic and had lost sphincteric control of the bladder and rectum. Rational patients complained bitterly of severe headache
ROSENOW EC, CALDWELL HW. STUDIES ON THE ETIOLOGY AND SERUM TREATMENT OF ENCEPHALITIS DURING THE EPIDEMIC IN NORTH DAKOTA AND MINNESOTA (1941)1. Ann Intern Med. ;17:474–485. doi: 10.7326/0003-4819-17-3-474
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Published: Ann Intern Med. 1942;17(3):474-485.
CNS Infections, Infectious Disease, Neurology.
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