The occurrence in man of infection with the fungus Coccidioides immitis has been recognized since the description of the first case by Wernicke and by Posadas in Argentina 50 years ago. Many similar cases (of the generalized form of the disease) have since been reported in the United States, over 500 in all, a large majority of whom had lived in the San Joaquin Valley in California. This disease, generally known as coccidioidal granuloma, is characterized by the development of extensive granulomatous and suppurative lesions, most frequently in the lungs, but also in other viscera, in the skin, bones and
COCCIDIOIDOMYCOSIS. Ann Intern Med. ;17:549–551. doi: 10.7326/0003-4819-17-3-549
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Published: Ann Intern Med. 1942;17(3):549-551.
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